Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | extremely low frequency electromagnetic fields affect the phosphoinositide signal transduction pathway by triggering the PI-PLC activation and the consequent phosphatidylinositol 4,5-bisphosphate breakdown | Peganum harmala |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine | potent inhibitor | Peganum harmala | |
neomycin | - |
Peganum harmala | |
U-73122 | - |
Peganum harmala |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O | Peganum harmala | part of the phosphoinositide signal transduction pathway | 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Peganum harmala | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
callus | 20 days old calli | Peganum harmala | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O | - |
Peganum harmala | 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol | - |
? | |
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O | part of the phosphoinositide signal transduction pathway | Peganum harmala | 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol | - |
? |