Literature summary for 3.1.4.1 extracted from

Bautista Nino, P.K.; Durik, M.; Danser, A.H.; de Vries, R.; Musterd-Bhaggoe, U.M.; Meima, M.E.; Kavousi, M.; Ghanbari, M.; Hoeijmakers, J.H.; O'Donnell, C.J.; Franceschini, N.; Janssen, G.M.; De Mey, J.G.; Liu, Y.; Shanahan, C.M.; Franco, O.H.; Dehghan, A.; Roks, A.J.
Phosphodiesterase 1 regulation is a key mechanism in vascular aging (2015), Clin. Sci., 129, 1061-1075 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
3-isobutyl-1-methyl xanthine	-	Homo sapiens
vinpocetine	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
vascular smooth muscle cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
PDE1	-	Homo sapiens
PDE1A	isoform	Homo sapiens
PDE1C	isoform	Homo sapiens
phosphodiesterase 1	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	genomic instability and cellular senescence in vascular smooth muscle cells increase enzyme expression	up

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Release 2023.1 (January 2023)