Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.3.95 extracted from

  • Hao, F.; Itoh, T.; Morita, E.; Shirahama-Noda, K.; Yoshimori, T.; Noda, T.
    The PtdIns3-phosphatase MTMR3 interacts with mTORC1 and suppresses its activity (2016), FEBS Lett., 590, 161-173 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.95

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293T cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
C413S inactive Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
Golgi apparatus
-
 Homo sapiens 5794
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Strep-Tactin Sepharose column chromatography Homo sapiens

Subunits

Subunits Comment Organism
? x * 150000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
MTMR3
-
 Homo sapiens
PtdIns3-phosphatase
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function overexpression of isoform MTMR3 inhibits the activity of the serine/threonine kinase complex mTORC1. Thus the enzyme regulates autophagy via its effect on mTORC1 activity Homo sapiens