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Literature summary for 3.1.3.9 extracted from

  • Singh, P.; Han, E.H.; Endrizzi, J.A.; OBrien, R.M.; Chi, Y.I.
    Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter (2017), J. Struct. Biol., 198, 54-64 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3)-Rosetta2 cells Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
FoxO1 DNA binding domain in complex with the G6PC1 promoter, hanging drop vapor diffusion method, using 14-18% (v/v) PEG 8000, 100 mM ammonium sulfate, 20 mM magnesium chloride, 50 mM MES pH 5.6 and 10% (v/v) glycerol Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-glucose 6-phosphate + H2O Homo sapiens
-
D-glucose + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glucose 6-phosphate + H2O
-
Homo sapiens D-glucose + phosphate
-
?

Synonyms

Synonyms Comment Organism
G6Pase
-
Homo sapiens
G6Pc1
-
Homo sapiens
G6Pc1 catalytic subunit gene 1 Homo sapiens