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Literature summary for 3.1.3.9 extracted from

  • Hirota, K.; Sakamaki, J.; Ishida, J.; Shimamoto, Y.; Nishihara, S.; Kodama, N.; Ohta, K.; Yamamoto, M.; Tanimoto, K.; Fukamizu, A.
    A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding (2008), J. Biol. Chem., 283, 32432-32441.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information Foxo1 synergizes with HNF-4 in activating the G6Pase gene transcription Mus musculus
additional information Foxo1 synergizes with HNF-4 in activating the G6Pase gene transcription Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Hep-G2, HeLa, and CV1 cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glucose 6-phosphate + H2O
-
Mus musculus D-glucose + phosphate
-
?
D-glucose 6-phosphate + H2O
-
Homo sapiens D-glucose + phosphate
-
?

Synonyms

Synonyms Comment Organism
G6Pase
-
Mus musculus
G6Pase
-
Homo sapiens