Cloned (Comment) | Organism |
---|---|
cloning into an andoviral vector of nontagged or FLAG-tagged beta-subunit, expression in COS-1 cells | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
vanadate | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Mus musculus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose 6-phosphate + H2O | Mus musculus | the brain functional glucose-6-phosphatase complex is capable of endogenous glucose production from glucose 6-phosphate, independent of blood glucose | D-glucose + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
two enzyme forms with different acid sensitivity and tissue location | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
astrocyte | primary | Mus musculus | - |
brain | contains a functional glucose-6-phosphatase complex capable of endogenous glucose production from glucose 6-phosphate, independent of blood glucose | Mus musculus | - |
heart | - |
Mus musculus | - |
intestine | - |
Mus musculus | - |
kidney | - |
Mus musculus | - |
liver | - |
Mus musculus | - |
additional information | expression of the enzyme and of glucose 6-phosphate transporter, overview, two enzyme forms: an acid-sensitive Glc-6-Pase-alpha in liver, kidney and intestine, and an acid-insensitive Glc-6-Pase-beta in astrocytes, overview | Mus musculus | - |
skeletal muscle | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Mus musculus |
0.011 | - |
brain | Mus musculus |
0.272 | - |
liver | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose 6-phosphate + H2O | - |
Mus musculus | D-glucose + phosphate | - |
? | |
D-glucose 6-phosphate + H2O | the brain functional glucose-6-phosphatase complex is capable of endogenous glucose production from glucose 6-phosphate, independent of blood glucose | Mus musculus | D-glucose + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Glc-6-P phosphohydrolase | - |
Mus musculus |
Glc-6-Pase-alpha | - |
Mus musculus |
Glc-6-Pase-beta | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
- |
Mus musculus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
two enzyme forms: an acid-sensitive Glc-6-Pase-alpha in liver, kidney and intestine, and an acid-insensitive Glc-6-Pase-beta in astroctyes | Mus musculus |