Literature summary for 3.1.3.9 extracted from

Hornbuckle, L.A.; Everett, C.A.; Martin, C.C.; Gustavson, S.S.; Svitek, C.A.; Oeser, J.K.; Neal, D.W.; Cherrington, A.D.; O'Brien, R.M.
Selective stimulation of G-6-Pase catalytic subunit but not G-6-P transporter gene expression by glucagon in vivo and cAMP in situ (2004), Am. J. Physiol., 286, E795-E808.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	selective stimulation of expression by glucagon in vivo and cAMP in situ, of recombinant enzyme catalytic subunit expressed in human Hep-G2 cells or native enzyme catalytic subunit in pancreatic-clamped or liver-clamped, euglycemic conscious dogs, overview	Canis lupus familiaris

Cloned(Commentary)

Cloned (Comment)	Organism
transient expression of the catalytic subunit in Hep-G2 cells	Canis lupus familiaris

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-glucose 6-phosphate + H2O	Canis lupus familiaris	the enzyme catalytic subunit expression is regulated independently from the glucose-6-phosphate transporter expression by metabolites, overview	D-glucose + phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Canis lupus familiaris	-	female and male mongrel dogs	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Canis lupus familiaris	-
pancreas	-	Canis lupus familiaris	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-glucose 6-phosphate + H2O	-	Canis lupus familiaris	D-glucose + phosphate	-	?
D-glucose 6-phosphate + H2O	the enzyme catalytic subunit expression is regulated independently from the glucose-6-phosphate transporter expression by metabolites, overview	Canis lupus familiaris	D-glucose + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
G-6-Pase	-	Canis lupus familiaris

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Release 2023.1 (January 2023)