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Literature summary for 3.1.3.77 extracted from
- Enolase-phosphatase 1 as a novel potential malignant glioma indicator promotes cell proliferation and migration (2018), Oncol. Rep., 40, 2233-2241 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | compared with normal brain tissues, the level of Enoph1 is markedly increased in glioma tissues. The glioma pathological grade is positively associated with the expression level of Enoph1. Knockdown of Enoph1 expression with siRNA markedly reduces cell proliferation, and significantly decreases cell migration. Knockdown of Enoph1 promotes its downstream protein, acireductone dioxygenase 1, to shift from the nucleus to the cytoplasm of U251 glioma cells, while membrane type 1-matrix metalloproteinase expression is significantly downregulated compared with the control group | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Homo sapiens | - |
| glioma cell | - |
Homo sapiens | - |
| U-251 cell | - |
Homo sapiens | - |
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Release 2023.1 (January 2023)
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