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Literature summary for 3.1.3.66 extracted from

  • Balakrishnan, A.; Chaillet, J.R.
    Role of the inositol polyphosphate-4-phosphatase type II Inpp4b in the generation of ovarian teratomas (2013), Dev. Biol., 373, 118-129.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
ovary cancer cell
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Mus musculus
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Synonyms

Synonyms Comment Organism
INPP4B
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Mus musculus

Expression

Organism Comment Expression
Mus musculus Tgkd allele is associated with a decrease in Inpp4b expression down

General Information

General Information Comment Organism
malfunction the insertion of Tgkd 3 of the Inpp4b gene is associated with decreased expression of Inpp4b and changes in intracellular PI3 Kinase/AKT signaling in follicular granulosa cells. This is associated with several follicular defects including oocytes trapped within luteinized follicles Mus musculus