Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O | Mus musculus | - |
1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O | - |
Mus musculus | 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
inositol polyphosphate 4-phosphatase 1 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | ananlysis of the role of 4-phosphatase I in the regulation of PtdIns(3,4)P2 in platelets in the weeble mouse model, the mice are viable, but lack platelet 4-phosphatase I, overview. Weeble chimeric mice have a propensity for thrombosis using a carotid artery injury model | Mus musculus |
physiological function | PtdIns(3,4)P2 is important for platelet function and stabilizes platelet aggregates, role of inositol polyphosphate 4-phosphatase 1 in regulation of PtdIns(3,4)P2 and of platelet function, overview | Mus musculus |