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Literature summary for 3.1.3.64 extracted from

  • Srivastava, S.; Li, Z.; Lin, L.; Liu, G.; Ko, K.; Coetzee, W.A.; Skolnik, E.Y.
    The phosphatidylinositol 3-phosphate phosphatase myotubularin-related protein 6 (MTMR6) is a negative regulator of the Ca2+-activated K+ channel KCa3.1 (2005), Mol. Cell. Biol., 25, 3630-3638.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
stable coexpression of human FLAG-tagged Ca2+-activated K+ channel KCa3.1 with GFP-tagged or FLAG-tagged MTMR6 in CHO cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O Homo sapiens
-
1-phosphatidyl-1D-myo-inositol + phosphate
-
?
additional information Homo sapiens MTMR6 is a negative regulator of the Ca2+-activated K+ channel KCa3.1 requiring MTMR6 enzyme activity with 1-phosphatidyl-1D-myo-inositol 3-phosphate, and the CC domain ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O
-
Homo sapiens 1-phosphatidyl-1D-myo-inositol + phosphate
-
?
additional information MTMR6 is a negative regulator of the Ca2+-activated K+ channel KCa3.1 requiring MTMR6 enzyme activity with 1-phosphatidyl-1D-myo-inositol 3-phosphate, and the CC domain Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
MTMR6
-
Homo sapiens
phosphatase myotubularin-related protein 6
-
Homo sapiens