Cloned (Comment) | Organism |
---|---|
cDNA encoding the adapter subunit 3-PAP of phosphatidylinositol 3-phosphate 3-phosphatase is cloned, sequenced and characterized, expression of 3-PAP in SF9 insect cells | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | platelet | Homo sapiens | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
86000 | - |
x * 86000 + x * ?, adapter subunit 3-PAP of phosphatidylinositol 3-phosphate phosphatase, forms a complex with a catalytic subunit of unknown MW, predicted from the amino acid sequence | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9C0I1 | adapter subunit 3-PAP of phosphatidylinositol 3-phosphate phosphatase | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | adapter subunit 3-PAP mRNA, 2 transcripts of 5.5 and 2.5 kb | Homo sapiens | - |
heart | adapter subunit 3-PAP mRNA, 2 transcripts of 5.5 and 2.5 kb | Homo sapiens | - |
kidney | adapter subunit 3-PAP mRNA, highest abundance in liver, kidney, lung and placenta, 2 transcripts of 5.5 and 2.5 kb | Homo sapiens | - |
liver | adapter subunit 3-PAP mRNA, highest abundance in liver, kidney, lung and placenta, 2 transcripts of 5.5 and 2.5 kb | Homo sapiens | - |
lung | adapter subunit 3-PAP mRNA, highest abundance in liver, kidney, lung and placenta, 2 transcripts of 5.5 and 2.5 kb | Homo sapiens | - |
placenta | adapter subunit 3-PAP mRNA, highest abundance in liver, kidney, lung and placenta, 2 transcripts of 5.5 and 2.5 kb | Homo sapiens | - |
platelet | isolation of adapter subunit 3-PAP immunoprecipitates | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | not: phosphatidylinositol 3,4,5-trisphosphate | Homo sapiens | ? | - |
? | |
additional information | the adapter subunit 3-PAP of phosphatidylinositol 3-phosphate phosphatase alone is catalytically inactive | Homo sapiens | ? | - |
? | |
phosphatidylinositol 3,4-bisphosphate + H2O | - |
Homo sapiens | phosphatidylinositol 4-phosphate + phosphate | - |
? | |
phosphatidylinositol 3-phosphate + H2O | - |
Homo sapiens | phosphatidylinositol + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | x * 86000 + x * ?, adapter subunit 3-PAP of phosphatidylinositol 3-phosphate phosphatase, forms a complex with a catalytic subunit of unknown MW, predicted from the amino acid sequence | Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Homo sapiens |