Literature summary for 3.1.3.62 extracted from

Yu, J.; Leibiger, B.; Yang, S.N.; Caffery, J.J.; Shears, S.B.; Leibiger, I.B.; Barker, C.J.; Berggren, P.O.
Cytosolic multiple inositol polyphosphate phosphatase in the regulation of cytoplasmic free Ca2+ concentration (2003), J. Biol. Chem., 278, 46210-46218.

Search for more literature for 3.1.3.62

Cloned(Commentary)

Cloned (Comment)	Organism
N-terminal truncated cytosolic MIPP is expressed in the beta-cell line HIT M2.2.2, expression increases the basal Ca2+-concentration to a more normal level	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	recombinant N-terminal truncated form lacking the ER signal peptide is cytosolic	Rattus norvegicus	5829	-
endoplasmic reticulum	largely endoplasmic reticulum-confined MIPP	Rattus norvegicus	5783	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O	recombinant N-terminal truncated cytosolic MIPP generates inositol 1,4,5-trisphosphate in an intact cell	Rattus norvegicus	D-myo-inositol 1,4,5-trisphosphate + phosphate	-	?
inositol 1,3,4,5,6-pentakisphosphate + H2O	recombinant N-terminal truncated cytosolic MIPP	Rattus norvegicus	inositol 1,4,5,6-tetrakisphosphate + phosphate	-	?
inositol hexakisphosphate + H2O	recombinant N-terminal truncated cytosolic MIPP	Rattus norvegicus	inositol pentakisphosphate + phosphate	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)