Cloned (Comment) | Organism |
---|---|
N-terminal truncated cytosolic MIPP is expressed in the beta-cell line HIT M2.2.2, expression increases the basal Ca2+-concentration to a more normal level | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | recombinant N-terminal truncated form lacking the ER signal peptide is cytosolic | Rattus norvegicus | 5829 | - |
endoplasmic reticulum | largely endoplasmic reticulum-confined MIPP | Rattus norvegicus | 5783 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O | recombinant N-terminal truncated cytosolic MIPP generates inositol 1,4,5-trisphosphate in an intact cell | Rattus norvegicus | D-myo-inositol 1,4,5-trisphosphate + phosphate | - |
? | |
inositol 1,3,4,5,6-pentakisphosphate + H2O | recombinant N-terminal truncated cytosolic MIPP | Rattus norvegicus | inositol 1,4,5,6-tetrakisphosphate + phosphate | - |
? | |
inositol hexakisphosphate + H2O | recombinant N-terminal truncated cytosolic MIPP | Rattus norvegicus | inositol pentakisphosphate + phosphate | - |
? |