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Literature summary for 3.1.3.62 extracted from

  • Hidaka, K.; Kanematsu, T.; Caffrey, J.J.; Takeuchi, H.; Shears, S.B.; Hirata, M.
    The importance to chondrocyte differentiation of changes in expression of the multiple inositol polyphosphate phosphatase (2003), Exp. Cell Res., 290, 254-264.
    View publication on PubMed
Search for more literature for 3.1.3.62

Cloned(Commentary)

Cloned (Comment) Organism
full-length Minpp cDNA is cloned and stably overexpressed in murine ATDC-5 cells at 2fold higher levels than in wild-type ATDC-5 cells, cellular effects of overexpression Homo sapiens
MINPP gene encoding multiple inositol polyphosphate phosphatase Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum recombinant Minpp expressed in murine ATDC-5 cells, only expressed inside the ER Homo sapiens 5783
-

Metals/Ions

Metals/Ions Comment Organism Structure
additional information Mg2+-independent Mus musculus
additional information Mg2+-independent Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Oryctolagus cuniculus
-
 ?
-
 ?
additional information Mus musculus Minpp is important to chondrocyte differentiation in a manner independent of inositol polyphosphate turnover ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
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Oryctolagus cuniculus
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 male Japanese white rabbits, 4 weeks old
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Source Tissue

Source Tissue Comment Organism Textmining
ATDC-5 cell chondrocyte progenitor cell line, developmentally specific changes in MINPP expression Mus musculus
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chondrocyte nonsynchronous primary cultures of growth plate chondrocytes from rib cartilage, developmentally specific changes in MINPP expression Oryctolagus cuniculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O
-
 Mus musculus D-myo-inositol 1,4,5-trisphosphate + phosphate
-
 ?
D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O
-
 Oryctolagus cuniculus D-myo-inositol 1,4,5-trisphosphate + phosphate
-
 ?
inositol 1,3,4,5,6-pentakisphosphate + H2O
-
 Mus musculus inositol 1,4,5,6-tetrakisphosphate + phosphate
-
 ?
inositol 1,3,4,5,6-pentakisphosphate + H2O
-
 Oryctolagus cuniculus inositol 1,4,5,6-tetrakisphosphate + phosphate
-
 ?
inositol hexakisphosphate + H2O
-
 Mus musculus inositol pentakisphosphate + phosphate
-
 ?
inositol hexakisphosphate + H2O
-
 Oryctolagus cuniculus inositol pentakisphosphate + phosphate
-
 ?
additional information
-
 Oryctolagus cuniculus ?
-
 ?
additional information dephosphorylates inositol signaling molecules InsP5 and InsP6 Mus musculus ?
-
 ?
additional information dephosphorylates inositol signaling molecules InsP5 and InsP6 Oryctolagus cuniculus ?
-
 ?
additional information Minpp is important to chondrocyte differentiation in a manner independent of inositol polyphosphate turnover Mus musculus ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mus musculus
37
-
 assay at Oryctolagus cuniculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Mus musculus
7.4
-
 assay at Oryctolagus cuniculus