Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,3-bisphosphoglycerate | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0011 | - |
D-myo-Inositol 1,3,4,5-tetrakisphosphate | type I enzyme, pH 7.5, 37°C | Sus scrofa | |
0.0089 | - |
D-myo-inositol 1,4,5-trisphosphate | type I enzyme, pH 7.5, 37°C | Sus scrofa | |
0.0714 | - |
D-myo-inositol 1,4,5-trisphosphate | type II enzyme, pH 7.5, 37°C | Sus scrofa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Sus scrofa | 16020 | - |
soluble | 83% of total activity | Sus scrofa | - |
- |
soluble | two different soluble enzymes, type I and type II | Sus scrofa | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
48000 | - |
SDS-PAGE, type I enzyme | Sus scrofa |
81000 | - |
gel filtration, type II enzyme | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O | Sus scrofa | - |
D-myo-inositol 1,3,4-trisphosphate + phosphate | - |
? | |
D-myo-inositol 1,4,5-trisphosphate + H2O | Sus scrofa | involved in regulation of excitation-contraction coupling in skeletal muscle | D-myo-inositol 1,4-bisphosphate + phosphate | - |
? | |
D-myo-inositol 1,4,5-trisphosphate + H2O | Sus scrofa | regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate | D-myo-inositol 1,4-bisphosphate + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
type I enzyme | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | skeletal muscle | Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
2.54 | - |
purified type I enzyme, pH 7.5, 37°C | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O | - |
Sus scrofa | D-myo-inositol 1,3,4-trisphosphate + phosphate | - |
? | |
D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O | type I and type II enzyme | Sus scrofa | D-myo-inositol 1,3,4-trisphosphate + phosphate | - |
? | |
D-myo-inositol 1,4,5-trisphosphate + H2O | - |
Sus scrofa | D-myo-inositol 1,4-bisphosphate + phosphate | - |
? | |
D-myo-inositol 1,4,5-trisphosphate + H2O | involved in regulation of excitation-contraction coupling in skeletal muscle | Sus scrofa | D-myo-inositol 1,4-bisphosphate + phosphate | - |
? | |
D-myo-inositol 1,4,5-trisphosphate + H2O | regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate | Sus scrofa | D-myo-inositol 1,4-bisphosphate + phosphate | - |
? |