Inhibitors | Comment | Organism | Structure |
---|---|---|---|
adenosine 5'-(alpha,beta-methylene)diphosphate | - |
Rattus norvegicus | |
ADP | - |
Rattus norvegicus | |
ATP | - |
Rattus norvegicus | |
Co2+ | inhibition of cytosolic and membrane-bound enzyme | Rattus norvegicus | |
Cu2+ | inhibition of cytosolic and membrane-bound enzyme | Rattus norvegicus | |
EDTA | inhibition of cytosolic and membrane-bound enzyme | Rattus norvegicus | |
Mn2+ | inhibition of cytosolic and membrane-bound enzyme | Rattus norvegicus | |
Zn2+ | inhibition of cytosolic and membrane-bound enzyme | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.048 | - |
5'-GMP | synaptic membrane-bound | Rattus norvegicus | |
0.048 | - |
5'-TMP | synaptic membrane-bound | Rattus norvegicus | |
0.056 | - |
5'-IMP | synaptic membrane-bound | Rattus norvegicus | |
0.074 | - |
5'-TMP | brain cytosol | Rattus norvegicus | |
0.083 | - |
5'-AMP | synaptic membrane-bound | Rattus norvegicus | |
0.09 | - |
5'-GMP | brain cytosol | Rattus norvegicus | |
0.09 | - |
5'-UMP | synaptic membrane-bound | Rattus norvegicus | |
0.14 | - |
5'-CMP | synaptic membrane-bound | Rattus norvegicus | |
0.18 | - |
5'-UMP | brain cytosol | Rattus norvegicus | |
0.19 | - |
5'-CMP | brain cytosol | Rattus norvegicus | |
0.2 | - |
5'-IMP | brain cytosol | Rattus norvegicus | |
0.27 | - |
5'-AMP | brain cytosol | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Rattus norvegicus | 5737 | - |
plasma membrane | - |
Rattus norvegicus | 5886 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
72000 | - |
x * 72000, synaptic plasma membrane, SDS-PAGE | Rattus norvegicus |
131000 | - |
x * 131000, brain cytosol, SDS-PAGE | Rattus norvegicus |
268000 | - |
brain cytosol, gel filtration | Rattus norvegicus |
286000 | - |
enzyme from synaptic plasma membrane, gel filtration | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | cytosolic and membrane-bound enzyme from brain are both glycoproteins | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
brain cytosol and synaptic plasma membrane | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
7.48 | - |
cytosolic enzyme from brain | Rattus norvegicus |
60.5 | - |
synaptic plasma membrane | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-AMP + H2O | - |
Rattus norvegicus | adenosine + phosphate | - |
? | |
5'-CMP + H2O | - |
Rattus norvegicus | cytidine + phosphate | - |
? | |
5'-dTMP + H2O | - |
Rattus norvegicus | deoxythymidine + phosphate | - |
? | |
5'-GMP + H2O | - |
Rattus norvegicus | guanosine + phosphate | - |
? | |
5'-IMP + H2O | - |
Rattus norvegicus | inosine + phosphate | - |
? | |
5'-UMP + H2O | - |
Rattus norvegicus | uridine + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 72000, synaptic plasma membrane, SDS-PAGE | Rattus norvegicus |
? | x * 131000, brain cytosol, SDS-PAGE | Rattus norvegicus |