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Literature summary for 3.1.3.5 extracted from

  • Shali, S.; Yu, J.; Zhang, X.; Wang, X.; Jin, Y.; Su, M.; Liao, X.; Yu, J.; Zhi, X.; Zhou, P.
    Ecto-5'-nucleotidase (CD73) is a potential target of hepatocellular carcinoma (2018), J. Cell. Physiol., 234, 10248-10259 .
    View publication on PubMed
Search for more literature for 3.1.3.5

Inhibitors

Inhibitors Comment Organism Structure
alpha,beta-methylene-ADP
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P21589
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
 Homo sapiens
-
hepatocellular carcinoma cell
-
 Homo sapiens
-
liver
-
 Homo sapiens
-
MHCC97-H cell
-
 Homo sapiens
-
SMMC-7721 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-AMP + H2O
-
 Homo sapiens adenosine + phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 73000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
CD73
-
 Homo sapiens
ecto-5'-nucleotidase
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme promotes hepatocellular carcinoma growth and metastasis and upregulates the expression of epithelial growth factor receptor in hepatocellular carcinoma Homo sapiens