Literature summary for 3.1.3.5 extracted from

Pedrazza, E.L.; Rico, E.P.; Senger, M.R.; Pedrazza, L.; Zimmermann, F.F.; Sarkis, J.J.; Bogo, M.R.; Bonan, C.D.
Ecto-nucleotidase pathway is altered by different treatments with fluoxetine and nortriptyline (2008), Eur. J. Pharmacol., 583, 18-25.

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Inhibitors

Inhibitors	Comment	Organism	Structure
clomipramine	enzymatic activity is decreased by the antidepressant clomipramine after in vitro exposure	Rattus norvegicus
fluoxetine	-	Rattus norvegicus
nortriptyline	-	Rattus norvegicus
sertraline	enzymatic activity is decreased by the antidepressant sertraline after in vitro exposure	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
cerebral cortex	-	Rattus norvegicus	-
hippocampus	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5'-AMP + H2O	-	Rattus norvegicus	adenosine + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
ecto-5'-nucleotidase	-	Rattus norvegicus

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Release 2023.1 (January 2023)