Literature summary for 3.1.3.5 extracted from

Sadej, R.; Inai, K.; Rajfur, Z.; Ostapkowicz, A.; Kohler, J.; Skladanowski, A.C.; Mitchell, B.S.; Spychala, J.
Tenascin C interacts with Ecto-5-nucleotidase (eN) and regulates adenosine generation in cancer cells (2008), Biochim. Biophys. Acta, 1782, 35-40.

Search for more literature for 3.1.3.5

Application

Application	Comment	Organism
medicine	ecto-5'-nucleotidase is a marker of ER (-) breast carcinoma and elevated expression correlates with invasive mesenchymal cell phenotype	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
concanavalin A	strong inhibitor	Homo sapiens
tenascin C	75.8% inhibition at 0.025 mg/ml	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
breast cancer cell	-	Homo sapiens	-
MDA-MB-231 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5'-AMP + H2O	-	Homo sapiens	adenosine + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
ecto-5'-nucleotidase	-	Homo sapiens

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Release 2023.1 (January 2023)