Literature summary for 3.1.3.5 extracted from

Levesque, S.A.; Lavoie, E.G.; Lecka, J.; Bigonnesse, F.; Sevigny, J.
Specificity of the ecto-ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases (2007), Br. J. Pharmacol., 152, 141-150.

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Inhibitors

Inhibitors	Comment	Organism	Structure
6-N,N-diethyl-D-beta-gamma-dibromomethylene adenosine triphosphate	originally named FPL 67156 or ARL 67156, 28% inhibition at 0.1 mM	Homo sapiens
ADP	40% inhibition at 0.1 mM	Homo sapiens
alpha,beta-methylene-ADP	highly effective competitive inhibitor	Homo sapiens
ATP	70% inhibition at 0.1 mM	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q53Z63	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5'-AMP + H2O	-	Homo sapiens	adenosine + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
ecto-5'-nucleotidase	-	Homo sapiens
ectonucleotidase	-	Homo sapiens

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Release 2023.1 (January 2023)