Literature summary for 3.1.3.5 extracted from

Braganhol, E.; Tamajusuku, A.S.; Bernardi, A.; Wink, M.R.; Battastini, A.M.
Ecto-5'-nucleotidase/CD73 inhibition by quercetin in the human U138MG glioma cell line (2007), Biochim. Biophys. Acta, 1770, 1352-1359.

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Inhibitors

Inhibitors	Comment	Organism	Structure
alpha,beta-methylene adenosine-5'-diphosphate	-	Homo sapiens
additional information	not inhibited by levamisole	Homo sapiens
quercetin	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
U-138MG cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5'-AMP + H2O	-	Homo sapiens	adenosine + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
ecto-5'-NT/CD73	-	Homo sapiens
ecto-5'-nucleotidase/CD73	-	Homo sapiens

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0453	-	pH 7.4, 37°C	Homo sapiens	quercetin

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Release 2023.1 (January 2023)