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Literature summary for 3.1.3.48 extracted from

  • Kapoor, S.; Girish, T.S.; Mandal, S.S.; Gopal, B.; Bhattacharyya, A.J.
    Inhibition of a protein tyrosine phosphatase using mesoporous oxides (2010), J. Phys. Chem. B, 114, 3117-3121.
    View publication on PubMed
Search for more literature for 3.1.3.48

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli strain BL21(DE3) Gallus gallus

Inhibitors

Inhibitors Comment Organism Structure
4-nitrocatechol sulfate applied from from bare and amine functionalized mesoporous silica, MCM-48, and mesoporous alumina for sustained delivery, competitive inhibition, kinetics, overview Gallus gallus

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
retina
-
 Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl phosphate + H2O
-
 Gallus gallus 4-nitrophenol + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
chick retinal tyrosine phosphatase-2
-
 Gallus gallus
Cryp-2
-
 Gallus gallus
CRYP-2/PTPRO
-
 Gallus gallus
CRYP-2/receptor-type tyrosine-protein phosphatase O
-
 Gallus gallus
More CRYP-2 is identical in sequence to the human glomerular epithelial protein-1 Gallus gallus
protein tyrosine phosphatase
-
 Gallus gallus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Gallus gallus

General Information

General Information Comment Organism
malfunction CRYP-2 is involved in hepatic carcinomas, inhibition of CRYP-2 is of tremendous therapeutic importance Gallus gallus