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Literature summary for 3.1.3.48 extracted from

  • Tabernero, L.; Aricescu, A.R.; Jones, E.Y.; Szedlacsek, S.E.
    Protein tyrosine phosphatases: structure-function relationships (2008), FEBS J., 275, 867-882.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Yersinia sp. 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens human LMW-PTP is critical in the regulation of mitogenic signalling and Rho-mediated cytoskeletal rearrangements after platelet derived growth factor stimulation ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Yersinia sp.
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lens LMW-PTP is the predominant tyrosine phosphatase expressed in lens Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information human LMW-PTP is critical in the regulation of mitogenic signalling and Rho-mediated cytoskeletal rearrangements after platelet derived growth factor stimulation Homo sapiens ?
-
?
phosphorylated EphA2 receptor + H2O
-
Homo sapiens EphA2 receptor + phosphate
-
?
phosphorylated p130Cas + H2O
-
Yersinia sp. p130Cas + phosphate
-
?
phosphorylated ZAP-70 + H2O
-
Homo sapiens ZAP-70 + phosphate
-
?

Synonyms

Synonyms Comment Organism
LMW-PTP
-
Homo sapiens
low molecular weight-PTP
-
Homo sapiens
protein tyrosine phosphatase
-
Homo sapiens
protein tyrosine phosphatase
-
Yersinia sp.
PTP
-
Homo sapiens
PTP
-
Yersinia sp.
YopH
-
Yersinia sp.