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Literature summary for 3.1.3.48 extracted from
- Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT) (2006), Brain Res., 1116, 50-57.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21 Codon Plus cells | Mus musculus |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D1074A | inactive | Mus musculus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 61000 | - |
recombinant GST-fusion protein, SDS-PAGE | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
| Mus musculus C57/BL6J | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| glutathione-Sepharose column chromatography | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| beta-TC6 cell | - |
Mus musculus | - |
| brain | - |
Mus musculus | - |
| MIN6-m9 cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | N-cadherin, VE-cadherin, desmoglein, alpha-catenin, beta-catenin, gamma-catenin, and alpha-actinin are not dephosphorylated by RPTPrho | Mus musculus | ? | - |
? |  |
| additional information | N-cadherin, VE-cadherin, desmoglein, alpha-catenin, beta-catenin, gamma-catenin, and alpha-actinin are not dephosphorylated by RPTPrho | Mus musculus C57/BL6J | ? | - |
? | |
| p120ctn + H2O | - |
Mus musculus | 120ctn + phosphate | - |
? | |
| p120ctn + H2O | - |
Mus musculus C57/BL6J | 120ctn + phosphate | - |
? | |
| phosphorylated E-cadherin + H2O | - |
Mus musculus | E-cadherin + phosphate | - |
? | |
| phosphorylated E-cadherin + H2O | - |
Mus musculus C57/BL6J | E-cadherin + phosphate | - |
? | |
| phosphotyrosine + H2O | - |
Mus musculus | tyrosine + phosphate | - |
? | |
| phosphotyrosine + H2O | - |
Mus musculus C57/BL6J | tyrosine + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| R2B phosphatase | - |
Mus musculus |
| receptor protein tyrosine phosphatase rho | - |
Mus musculus |
| RPTPrho/PTPRT | - |
Mus musculus |
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Release 2023.1 (January 2023)
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