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Literature summary for 3.1.3.46 extracted from

  • Van Schaftingen, E.; Hers, H.G.
    Purification and properties of phosphofructokinase 2/fructose 2,6-bisphosphatase from chicken liver and from pigeon muscle (1986), Eur. J. Biochem., 159, 359-365.
    View publication on PubMed
Search for more literature for 3.1.3.46

Activating Compound

Activating Compound Comment Organism Structure
ATP
-
 Gallus gallus
Cyclic AMP dependent protein kinase activation Gallus gallus

Inhibitors

Inhibitors Comment Organism Structure
fructose 6-phosphate
-
 Gallus gallus
fructose 6-phosphate
-
 Pigeon
phosphate
-
 Gallus gallus
phosphate
-
 Pigeon

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0001
-
 fructose 2,6-bisphosphate
-
 Gallus gallus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
53000
-
 2 * 53000, SDS-PAGE Pigeon
54000
-
 2 * 54000, SDS-PAGE Gallus gallus
100000
-
 gel filtration Gallus gallus
100000
-
 gel filtration Pigeon

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
fructose 2,6-bisphosphate + H2O Gallus gallus
-
 ?
-
 ?
fructose 2,6-bisphosphate + H2O Pigeon
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-
Pigeon
-
-
-

Purification (Commentary)

Purification (Comment) Organism
bifunctional enzyme, copurification with phosphofructokinase 2 Gallus gallus
bifunctional enzyme, copurification with phosphofructokinase 2 Pigeon

Reaction

Reaction Comment Organism Reaction ID
beta-D-fructose 2,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate bifunctional enzyme: 6-phosphofructo-2-kinase-fructose-2,6-bisphosphatase Gallus gallus
a
beta-D-fructose 2,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate bifunctional enzyme: 6-phosphofructo-2-kinase-fructose-2,6-bisphosphatase Pigeon
a

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Gallus gallus
-
muscle breast Gallus gallus
-
muscle breast Pigeon
-

Storage Stability

Storage Stability Organism
-80°C, 20% glycerol, 200 mM KCl, 1 mM dithiothreitol, 20 mM Hepes, pH 7.1 Gallus gallus
-80°C, 20% glycerol, 200 mM KCl, 1 mM dithiothreitol, 20 mM Hepes, pH 7.1 Pigeon

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fructose 2,6-bisphosphate + H2O
-
 Gallus gallus fructose 6-phosphate + phosphate
-
 ?
fructose 2,6-bisphosphate + H2O
-
 Pigeon fructose 6-phosphate + phosphate
-
 ?
fructose 2,6-bisphosphate + H2O
-
 Gallus gallus ?
-
 ?
fructose 2,6-bisphosphate + H2O
-
 Pigeon ?
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 53000, SDS-PAGE Pigeon
dimer 2 * 54000, SDS-PAGE Gallus gallus