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Literature summary for 3.1.3.46 extracted from

  • You, E.J.; Khil, L.Y.; Kwak, W.J.; Won, H.S.; Chae, S.H.; Lee, B.H.; Moon, C.K.
    Effects of brazilin on the production of fructose-2,6-bisphosphate in rat hepatocytes (2005), J. Ethnopharmacol., 102, 53-57.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
brazilin a component isolated from Caesalpinia sappan wood, increases enzyme activity by increasing the cellular content of fructose-2,6-bishosphate via increased levels of fructose 6-phosphate and hexose 6-phosphate produced by activates 6-phosphofructo-2-kinase and pyruvate kinase, overview Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
beta-D-fructose 2,6-bisphosphate + H2O Rattus norvegicus
-
D-fructose 6-phosphate + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte primary Rattus norvegicus
-
liver
-
Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.000011
-
hepatocyte Rattus norvegicus
0.000014
-
hepatocyte treated with brazilin Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-D-fructose 2,6-bisphosphate + H2O
-
Rattus norvegicus D-fructose 6-phosphate + phosphate
-
?

Synonyms

Synonyms Comment Organism
More cf. EC 2.7.1.105 Rattus norvegicus
Pfk-2
-
Rattus norvegicus