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Literature summary for 3.1.3.43 extracted from

  • Beatty, S.M.; Hamilton, G.A.
    Inhibition of pyruvate dehydrogenase and pyruvate dehydrogenase phosphate phosphatase by glyoxylate (1985), Bioorg. Chem., 13, 14-23.
No PubMed abstract available
Search for more literature for 3.1.3.43

Activating Compound

Activating Compound Comment Organism Structure
cysteine reverses glyoxylate inhibition Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
glyoxylate at concentrations greater than 0.05 mM Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
 Rattus norvegicus
Mg2+
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O Rattus norvegicus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adipose
-
 Rattus norvegicus
-
epididymis
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O
-
 Rattus norvegicus [pyruvate dehydrogenase (lipoamide)] + phosphate
-
 ir
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O
-
 Rattus norvegicus ?
-
 ?