Literature summary for 3.1.3.43 extracted from

Piccinini, M.; Mostert, M.; Alberto, G.; Ramondetti, C.; Novi, R.F.; Dalmasso, P.; Rinaudo, M.T.
Down-regulation of pyruvate dehydrogenase phosphatase in obese subjects is a defect that signals insulin resistance (2005), Obes. Res., 13, 678-686.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O	Homo sapiens	-	[pyruvate dehydrogenase (lipoamide)] + phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lymphocyte	PDP1 is downregulated in obese subjects	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O	-	Homo sapiens	[pyruvate dehydrogenase (lipoamide)] + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
PDP1	-	Homo sapiens
pyruvate dehydrogenase phosphatase	-	Homo sapiens

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Release 2023.1 (January 2023)