Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | 5 mM, 2.4fold activation | Rattus norvegicus | |
D-glucosamine 6-phosphate | 2 mM, 30°C, pH 7.8, 3.2fold activation | Rattus norvegicus | |
D-glucose 1-phosphate | 2 mM, 30°C, pH 7.8, 3.8fold activation | Rattus norvegicus | |
D-glucose 6-phosphate | 4.9fold activation, without D-glucose 6-phosphate 38.8% remainimng activity and additionally without D-glucose 6-phosphate 23.1% remaining activity | Rattus norvegicus | |
Mg2+ | 5 mM, 3.7fold activation, without Mg2+ 33% remaining activity and additionally without D-glucose 6-phosphate 23.1% remaining activity | Rattus norvegicus | |
Mn2+ | 5 mM, 4.4fold activation | Rattus norvegicus | |
additional information | no effects of 5 mM K+ and Na+, and 2 mM 6-P-gluconate, D-fructose 1,6-bisphosphate, alpha-glycerol phosphate, creatine phosphate, phosphate, and SO42- | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
glycogen | competitive inhibition with glycogen synthase D as substrate | Rattus norvegicus | |
KF | 50 mM, 30°C, pH 7.8, complete inhibition | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphoprotein phosphatase + H2O | Rattus norvegicus | - |
protein + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycogen synthase D + H2O | - |
Rattus norvegicus | glycogen synthase I + phosphate | - |
? | |
phosphoprotein phosphatase + H2O | - |
Rattus norvegicus | protein + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glycogen synthase phosphatase | - |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.3 | - |
at 30°C | Rattus norvegicus |