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Literature summary for 3.1.3.4 extracted from
- Involvement of phosphatidate phosphohydrolase in arachidonic acid mobilization in human amniotic WISH cells (1998), J. Biol. Chem., 273, 7684-7690.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | activation of cytosolic phospholipase A 2 and attendant arachidonic acid release by phorbol esters in WISH cells requires prior generation of diacylglycerol by phosphatidate phosphohydrolase | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| WISH cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | activation of cytosolic phospholipase A 2 and attendant arachidonic acid release by phorbol esters in WISH cells requires prior generation of diacylglycerol by phosphatidate phosphohydrolase | Homo sapiens | ? | - |
? | |
| phosphatidic acid + H2O | - |
Homo sapiens | 1,2-diacyl-sn-glycerol + phosphate | - |
? | |
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