Activating Compound | Comment | Organism | Structure |
---|---|---|---|
polyamines | activate in presence of Mg2+, no activation in absence of Mg2+ | Rattus norvegicus | |
putrescine | activate in presence of Mg2+, no activation in absence of Mg2+. Effective at 2-5 mM | Rattus norvegicus | |
spermidine | activates in presence of Mg2+, no activation in absence of Mg2+. Effective at 1 mM | Rattus norvegicus | |
spermine | activates in presence of Mg2+, no activation in absence of Mg2+. Effective at 0.5-1 mM, inhibitory at higher concentrations | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
spermine | above 1 mM | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.098 | - |
phosphatidic acid | in presence of various polyamines | Rattus norvegicus | |
0.16 | - |
phosphatidic acid | without polyamines | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphatidic acid + H2O | - |
Rattus norvegicus | 1,2-diacyl-sn-glycerol + phosphate | - |
? |