Protein Variants | Comment | Organism |
---|---|---|
D319A | inactive mutant bearing a mutation in 5-phosphatase catalytic domain. This mutant is not able to restore dd5p4-null cells | Dictyostelium discoideum |
DELTARhoGAPDd5P4 | transfection of dd5p4-null cells with a truncated Dd5P4 lacking the C-terminal RhoGAP domain does not restore endocytic defects, suggesting that the C-terminal RhoGAP domain is essential | Dictyostelium discoideum |
additional information | expression of the human homolog OCRL (oculocerebrorenal syndrome of Lowe) in Dictyostelium discoideum dd5p4-null cells shows that expression of OCRL largely restores phagocytosis, growth and developmental defects of dd5p4-null cells, indicating that human OCRL can functionally replace Dictyostelium Dd5P4 | Dictyostelium discoideum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Dictyostelium discoideum | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
Dd5P4 | - |
Dictyostelium discoideum |