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Literature summary for 3.1.3.36 extracted from

  • Perera, R.M.; Zoncu, R.; Lucast, L.; De Camilli, P.; Toomre, D.
    Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages (2006), Proc. Natl. Acad. Sci. USA, 103, 19332-19337.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
molecular biology results raise the possibility that dynamic phosphoinositide metabolism may occur throughout the lifetime of a clathrin-coated pit Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
full-length SJ1-145 is cloned into the peGFP-C1 vector Homo sapiens
full-length SJ1-170 is cloned into the peGFP-C1 vector Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
clathrin-coated vesicle multicolor total internal reflection fluorescence microscopy (TIRFM) is used to visualize the spatial-temporal recruitment of SJ1, and its binding partner endophilin to clathrin-coated-pits. Differential temporal recruitment of the two major SJ1 splice variants to clathrin-coated-pits is observed. SJ1-145 is rapidly recruited as a burst, together with its binding partner endophilin, at a late stage of clathrin-coated-pit formation Homo sapiens 30136
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clathrin-coated vesicle multicolor total internal reflection fluorescence microscopy (TIRFM) is used to visualize the spatialtemporal recruitment of SJ1, and its binding partner endophilin to clathrin-coated-pits. Differential temporal recruitment of the two major SJ1 splice variants to clathrin-coated-pits is observed. SJ1-170 is present at all stages of CCP formation Homo sapiens 30136
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Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
145000
-
-
Homo sapiens
170000
-
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain ubiquitously expressed but predominant in brain Homo sapiens
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additional information ubiquitously expressed Homo sapiens
-

Synonyms

Synonyms Comment Organism
SJ1-145
-
Homo sapiens
SJ1-170
-
Homo sapiens
synaptojanin 1
-
Homo sapiens