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Literature summary for 3.1.3.32 extracted from

  • Habraken, Y.; Verly, W.G.
    Chromatin 3-phosphatase/5-OH kinase cannot transfer phosphate from 3 to 5 across a strand nick in DNA (1986), Nucleic Acids Res., 14, 8103-8110.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
chromatin
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Rattus norvegicus 785
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phopsho-5'-hydroxy-DNA Rattus norvegicus the enzyme is capable of converting a 3'-phosphate/5'-OH strand of nicked DNA, which is unreparable by DNA ligase into a reparable 3'-OH/5'-phosphate nick in double stranded DNA ?
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
enzyme also is polynucleotide 5'-hydroxyl kinase
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Purification (Commentary)

Purification (Comment) Organism
enzyme also is polynucleotide 5'-hydroxyl kinase Rattus norvegicus

Reaction

Reaction Comment Organism Reaction ID
a 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate also 5-hydroxylkinase activity Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phopsho-5'-hydroxy-DNA the enzyme is capable of converting a 3'-phosphate/5'-OH strand of nicked DNA, which is unreparable by DNA ligase into a reparable 3'-OH/5'-phosphate nick in double stranded DNA Rattus norvegicus ?
-
?
3'-phospho-5'-hydroxy-poly(dT,dA) + H2O poly(dT,dA) with a 3' phosphate and and 5' OH group, preparation of substrate, presence of ATP Rattus norvegicus 3'-hydroxy-5'-phospho-poly(dT,dA)
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?