Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Mycobacterium tuberculosis |
Crystallization (Comment) | Organism |
---|---|
hanging drop vapour diffusion method with in 10-14% (v/v) 2-methyl-2,4-pentanediol, 0.1 M tri-sodium citrate, pH 5.6, and 0.2 M ammonium acetate | Mycobacterium tuberculosis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Li+ | inhibitory, but can amplify the effect of Mg2+ | Mycobacterium tuberculosis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Li+ | activates only in the presence of Mg2+ | Mycobacterium tuberculosis | |
Mg2+ | activator | Mycobacterium tuberculosis |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
30508 | - |
1 * 30508, analytical ultracentrifugation, SuhB is predominantly monomeric in the absence of the physiological activator Mg2+ | Mycobacterium tuberculosis |
30508 | - |
2 * 30508, analytical ultracentrifugation, dimer in the presence of Mg2+ and in the crystal | Mycobacterium tuberculosis |
30510 | - |
analytical ultracentrifugation | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Sephacryl S200-HR gel filtration | Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycerol 2-phosphate + H2O | - |
Mycobacterium tuberculosis | glycerol + phosphate | - |
? | |
L-myo-inositol 1-phosphate + H2O | - |
Mycobacterium tuberculosis | L-myo-inositol + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 30508, analytical ultracentrifugation, dimer in the presence of Mg2+ and in the crystal | Mycobacterium tuberculosis |
monomer | 1 * 30508, analytical ultracentrifugation, SuhB is predominantly monomeric in the absence of the physiological activator Mg2+ | Mycobacterium tuberculosis |
Synonyms | Comment | Organism |
---|---|---|
IMPase | - |
Mycobacterium tuberculosis |
inositol monophosphatase | - |
Mycobacterium tuberculosis |
myo-inositol-1-phosphate phosphohydrolase | - |
Mycobacterium tuberculosis |
SuhB | - |
Mycobacterium tuberculosis |