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Literature summary for 3.1.3.25 extracted from

  • Hallcher, L.M.; Sherman, W.R.
    The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain (1980), J. Biol. Chem., 255, 10896-10901.
    View publication on PubMed
Search for more literature for 3.1.3.25

Activating Compound

Activating Compound Comment Organism Structure
NH4+ stimulatory Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
Ca2+
-
 Bos taurus
F- 50% inhibitory at 1 mM Bos taurus
Li+
-
 Bos taurus
Mn2+
-
 Bos taurus
SO42- 40% inhibitory at 17 mM Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.1
-
 L-myo-Inositol 1-phosphate
-
 Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ 3% activation at 3.5 mM Bos taurus
Co2+ 3% activation at 3.5 mM Bos taurus
Cu2+ 3% activation at 3.5 mM Bos taurus
Fe2+ 3% activation at 3.5 mM Bos taurus
K+
-
 Bos taurus
Mg2+ completely dependent on Bos taurus
Mn2+ 3% activation at 3.5 mM Bos taurus
Na+
-
 Bos taurus
NH4+ stimulatory Bos taurus
Zn2+ activation at 3.5 mM Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
58000
-
 gel filtration Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-AMP + H2O
-
 Bos taurus adenosine + phosphate
-
 ?
L-chiro-inositol-3-phosphate + H2O
-
 Bos taurus ?
-
 ?
additional information triphosphoinositide Bos taurus ?
-
 ?
myo-inositol 3-phosphate + H2O
-
 Bos taurus myo-inositol + phosphate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5 8
-
 Bos taurus