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Literature summary for 3.1.3.2 extracted from
- Localisation of high acid phosphotyrosine phosphatase activity in afferent arterioles and glomeruli of human kidney (2005), J. Mol. Histol., 36, 225-233.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | the lymphocytic enzyme is fluoride-resistant, the osteoclast enzyme is tartrate-resistant | Homo sapiens | |
| vanadate | lymphocytic enzyme | Homo sapiens |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Homo sapiens | 5737 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phospho-L-tyrosine + H2O | Homo sapiens | - |
L-tyrosine + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adrenal cortex | sinusoidal cells | Homo sapiens | - |
| adrenal gland | capsular small arteries of the endothelium | Homo sapiens | - |
| alveolar macrophage | - |
Homo sapiens | - |
| arteriole | interlobular | Homo sapiens | - |
| decidual cell | - |
Homo sapiens | - |
| endothelial cell | - |
Homo sapiens | - |
| endothelium | - |
Homo sapiens | - |
| intestinal wall | - |
Homo sapiens | - |
| kidney | cortical capillaries, medulla, glomeruli, distribution | Homo sapiens | - |
| liver | sinusoidal cells | Homo sapiens | - |
| liver sinusoidal endothelial cell | - |
Homo sapiens | - |
| lung | - |
Homo sapiens | - |
| lymph node | - |
Homo sapiens | - |
| lymphocyte | - |
Homo sapiens | - |
| macrophage | - |
Homo sapiens | - |
| mesangial cell | - |
Homo sapiens | - |
| additional information | tissue distribution of enzyme activity, overview | Homo sapiens | - |
| osteoclast | - |
Homo sapiens | - |
| renal glomerulus | - |
Homo sapiens | - |
| renal outer medulla | - |
Homo sapiens | - |
| spleen | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phospho-L-tyrosine + H2O | - |
Homo sapiens | L-tyrosine + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| acid phosphotyrosine phosphatase | - |
Homo sapiens |
| phosphotyrosine phosphatase | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5 | - |
assay at | Homo sapiens |
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