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Literature summary for 3.1.3.16 extracted from

  • Zhao, L.; Lu, Z.; He, X.; Mughal, M.; Fang, R.; Zhou, Y.; Zhao, J.; Gasser, R.; Grevelding, C.; Ye, Q.; Hu, M.
    Serine/threonine protein phosphatase 1 (PP1) controls growth and reproduction in Schistosoma japonicum (2018), FASEB J., 32, 6626-6642 .
    View publication on PubMed
Search for more literature for 3.1.3.16

Cloned(Commentary)

Cloned (Comment) Organism
gene Sj-PP1c-2, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative RT-PCR expression analysis Schistosoma japonicum
gene Sj-PP1c-3, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative RT-PCR expression analysis Schistosoma japonicum
genes Sj-PP1c-1 or PP1, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative RT-PCR expression analysis Schistosoma japonicum

Protein Variants

Protein Variants Comment Organism
additional information RNAi-mediated knockdown of the three Sj-pp1c genes, phenotypes, overview. Knockdown of the three Sj-pp1cs causes wide-ranging transcriptional changes in both sexes Schistosoma japonicum

Organism

Organism UniProt Comment Textmining
Schistosoma japonicum A0A291FAL7 gene Sj-pp1c-1 or PP1
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Schistosoma japonicum Q5DAL5 gene Sj-pp1c-3
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Schistosoma japonicum Q5FX73 gene Sj-pp1c-2 or ppp1cc
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Source Tissue

Source Tissue Comment Organism Textmining
additional information transcripts of the three Sj-pp1c genes mainly localize in the reproductive organs and tissues Schistosoma japonicum
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additional information transcripts of the three Sj-pp1c genes mainly localize in the reproductive organs and tissues, determination of the localization of Sj-pp1c transcripts by in situ hybridization Schistosoma japonicum
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Synonyms

Synonyms Comment Organism
PP!
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 Schistosoma japonicum
PP1
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 Schistosoma japonicum
PPP1CC
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 Schistosoma japonicum
serine/threonine protein phosphatase 1
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 Schistosoma japonicum
Sj-pp1c-1
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 Schistosoma japonicum
Sj-pp1c-2
-
 Schistosoma japonicum
Sj-pp1c-3
-
 Schistosoma japonicum

General Information

General Information Comment Organism
malfunction triple knockdown of Sj-pp1c genes by RNA interference causes stunted growth and decreased pairing stability of worm pairs, as well as a remarkable reduction in cell proliferation activity and defects in reproductive maturation and fecundity, phenotypes, overview Schistosoma japonicum
additional information transcriptomic analysis Schistosoma japonicum
physiological function the Sj-pp1c genes are involved in controlling worm development and maturation mainly by regulating cell proliferation, eggshell synthesis, nutritional metabolism, cytoskeleton organization, and neural process. Fundamental contribution of Sj-PP1c to molecular mechanisms underlying the reproductive biology of schistosomes Schistosoma japonicum
physiological function the Sj-pp1c genes are involved in controlling wormdevelopment and maturation mainly by regulating cell proliferation, eggshell synthesis, nutritional metabolism, cytoskeleton organization, and neural process. Fundamental contribution of Sj-PP1c to molecular mechanisms underlying the reproductive biology of schistosomes Schistosoma japonicum