Literature summary for 3.1.3.16 extracted from

Ilinykh, P.A.; Tigabu, B.; Ivanov, A.; Ammosova, T.; Obukhov, Y.; Garron, T.; Kumari, N.; Kovalskyy, D.; Platonov, M.O.; Naumchik, V.S.; Freiberg, A.N.; Nekhai, S.; Bukreyev, A.
Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription (2014), J. Biol. Chem., 289, 22723-22738.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in HEK-293T cells	Ebola virus sp.

Inhibitors

Inhibitors	Comment	Organism	Structure
1-[(ethylcarbamoyl)amino]-1-oxopropan-2-yl (3E)-3-(3,4-dimethoxybenzylidene)-2,3-dihydro-1H-cyclopenta[b]quinoline-9-carboxylate	-	Ebola virus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
phosphorylated Ebola virus VP30 protein + H2O	Ebola virus sp.	-	Ebola virus VP30 protein + phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Ebola virus sp.	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
phosphorylated Ebola virus VP30 protein + H2O	-	Ebola virus sp.	Ebola virus VP30 protein + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
PP1	-	Ebola virus sp.
protein phosphatase 1	-	Ebola virus sp.
SIPP1	a cytoplasm-shuttling regulatory subunit of protein phosphatase 1	Ebola virus sp.

General Information

General Information	Comment	Organism
physiological function	cytoplasmic accumulation of the enzyme induces Ebola virus transcription	Ebola virus sp.

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Release 2023.1 (January 2023)