Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Calmodulin | calcineurin is a Ca2+/calmodulin-activated Ser/Thr phosphatase | Caenorhabditis elegans |
Cloned (Comment) | Organism |
---|---|
co-expression of cacineurin with HLH-11 and interaction analysis using the yeast two-hybrid system | Caenorhabditis elegans |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | calcineurin is a Ca2+/calmodulin-activated Ser/Thr phosphatase | Caenorhabditis elegans |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | - |
subunits A and B are encoded by genes tax-6 and cnb-1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | HLH-11, a member of basic helix-loop-helix proteins, binds to calcineurin catalytic subunit Tax-6, probably regulating TAX-6 as a transcription factor and/or a functional regulator. HLH-11 is involved in regulation of many developmental processes such as cell proliferation and differentiation, sex determination and myogenesis, HLH-11 deletion phenotype, overview | Caenorhabditis elegans | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterodimer | - |
Caenorhabditis elegans |
Synonyms | Comment | Organism |
---|---|---|
calcineurin | - |
Caenorhabditis elegans |
General Information | Comment | Organism |
---|---|---|
physiological function | calcineurin play roles in various signaling pathways such as fertility, movement, body size regulation and serotonin-mediated egg laying | Caenorhabditis elegans |