Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the hypothetic mechanisms of carcinogenesis include a direct effect of calcineurin inhibitors on keratinocytes, because topical calcineurin inhibits DNA repair and reduces apoptosis in epidermal keratinocytes | Homo sapiens | |
pimecrolimus | a topical calcineurin inhibitor, treatement might bear high risk for skin cancer and lymphoma, overview | Homo sapiens | |
tacrolimus | a topical calcineurin inhibitor, treatment might bear high risk for skin cancer and lymphoma, overview | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
keratinocyte | epidermal | Homo sapiens | - |
lymphoma cell | - |
Homo sapiens | - |
skin cancer cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
calcineurin | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | topical calcineurin inhibits DNA repair and reduces apoptosis in epidermal keratinocytes | Homo sapiens |