Application | Comment | Organism |
---|---|---|
medicine | PP4 regulates both apoptosis and proliferation in human cells and the level of PP4 has a strong influence on gene mutation rate, which is crucial to oncogenesis | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expressed in HEK-293T cells, PP4c over-expressing cells are consistently more sensitive to UV-, cisplatin-, butyrate- and okadaic acid-induced cell death | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | some PP4c is cytoplasmic | Homo sapiens | 5737 | - |
nucleus | the subcellular localisation of PP4c is mainly nuclear | Homo sapiens | 5634 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
35000 | - |
catalytic subunit PP4c, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphoprotein + H2O | - |
Homo sapiens | protein + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Pp4 | - |
Homo sapiens |
PP4c | catalytic subunit of protein phosphatase 4 | Homo sapiens |
protein phosphatase 4 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
Calmodulin | - |
Homo sapiens |