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Literature summary for 3.1.3.16 extracted from

  • Liu, L.; Zhang, J.; Yuan, J.; Dang, Y.; Yang, C.; Chen, X.; Xu, J.; Yu, L.
    Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis (2005), Mol. Biol. Rep., 32, 41-45.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
isozyme PPP3R2, DNA and amino acid sequence determination and analysis, chromosome mapping to 9q22 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ the regulatory subunit is an EF-hand Ca2+-binding protein Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is critical in many calcium-dependent signaling transduction pathways ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q96LZ3 protein phosphatase 3 regulatory subunit B beta isoform; gene PPP3RL, two isozymes PPP3R1 and PPP3R2
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information isozyme PPP3R1 is ubiquitously expressed in tissues Homo sapiens
-
testis exclusive expression of isozyme PPP3R2 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is critical in many calcium-dependent signaling transduction pathways Homo sapiens ?
-
?

Subunits

Subunits Comment Organism
dimer the enzyme is composed of a catalytic subunit and a regulatory subunit, the latter is an EF-hand Ca2+-binding protein Homo sapiens

Synonyms

Synonyms Comment Organism
calcineurin
-
Homo sapiens
calcineurin B-like protein
-
Homo sapiens
CBLP
-
Homo sapiens
CNBII
-
Homo sapiens
More formerly PP2B Homo sapiens
PPP3
-
Homo sapiens
PPP3R-like protein
-
Homo sapiens
PPP3RL
-
Homo sapiens
protein phosphatase 3
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Homo sapiens