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Literature summary for 3.1.3.16 extracted from

  • Inostroza, J.; Saenz, L.; Calaf, G.; Cabello, G.; Parra, E.
    Role of the phosphatase PP4 in the activation of JNK-1 in prostate carcinoma cell lines PC-3 and LNCaP resulting in increased AP-1 and EGR-1 activity (2005), Biol. Res., 38, 163-178.
    View publication on PubMed
Search for more literature for 3.1.3.16

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
 Homo sapiens 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens PP4 activates c-Jun N-terminal kinase JNK-1 and is required for JNK-1 stability in prostate cancer cells, PP4 is involved in the MAPK signaling pathway, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
DU-145 cell
-
 Homo sapiens
-
LNCaP cell prostate cancer cell line Homo sapiens
-
additional information PP4 is expressed in various cancer cell lines Homo sapiens
-
PC-3 cell prostate cancer cell line Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PP4 activates c-Jun N-terminal kinase JNK-1 and is required for JNK-1 stability in prostate cancer cells, PP4 is involved in the MAPK signaling pathway, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
phosphatase PP4
-
 Homo sapiens
serine/threonine phosphatase
-
 Homo sapiens