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Literature summary for 3.1.3.16 extracted from
- Identification, purification, and characterization of a novel serine/threonine protein phosphatase from bovine brain (1991), J. Biol. Chem., 266, 6614-6619.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Inhibitor-2 | stimulation of phosphatase PP3 | Bos taurus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| microcystin-LR | inhibition of phosphatase PP3 | Bos taurus |  |
| okadaic acid | inhibition of phosphatase PP3 | Bos taurus | |
| protamine | inhibition of phosphatase PP3 | Bos taurus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | phosphatase PP3 | Bos taurus | 16020 | - |
| membrane | appears to be an integral membrane protein | Bos taurus | 16020 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | phosphatase PP3 active in the absence of divalent cations | Bos taurus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 33000 | - |
membrane-bound phosphatase PP3, SDS-PAGE | Bos taurus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phosphoprotein + H2O | Bos taurus | phosphatase PP3 stimulates the initiation of DNA-synthesis | protein + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| catalytic subunit of PP3 | Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | phosphatase PP3 | Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phosphohistone + H2O | - |
Bos taurus | histone + phosphate | - |
? | |
| phosphoprotein + H2O | phosphatase PP3 stimulates the initiation of DNA-synthesis | Bos taurus | protein + phosphate | - |
? | |
| phosphoproteins + H2O | - |
Bos taurus | proteins + phosphate | - |
? | |
| phosphorylase a + H2O | - |
Bos taurus | phosphorylase b + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PP3 | - |
Bos taurus |
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