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Literature summary for 3.1.3.15 extracted from
- Expression, purification and preliminary X-ray characterization of histidinol phosphate phosphatase (2004), Acta Crystallogr. Sect. D, 60, 574-576.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Thermus thermophilus |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| two crystal forms by the handing-drop vapour-diffusion technique | Thermus thermophilus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 29976 | - |
4 * 29976 | Thermus thermophilus |
| 92000 | - |
gel filtration | Thermus thermophilus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-histidinol phosphate + H2O | Thermus thermophilus | the enzyme catalyses the eigthth step of histidine biosynthesis | L-histidinol + phosphate | - |
? |  |
| L-histidinol phosphate + H2O | Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | the enzyme catalyses the eigthth step of histidine biosynthesis | L-histidinol + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Thermus thermophilus | - |
HB8 | - |
| Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | - |
HB8 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| the recombinant enzyme | Thermus thermophilus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-histidinol phosphate + H2O | - |
Thermus thermophilus | L-histidinol + phosphate | - |
? | |
| L-histidinol phosphate + H2O | the enzyme catalyses the eigthth step of histidine biosynthesis | Thermus thermophilus | L-histidinol + phosphate | - |
? | |
| L-histidinol phosphate + H2O | - |
Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | L-histidinol + phosphate | - |
? | |
| L-histidinol phosphate + H2O | the enzyme catalyses the eigthth step of histidine biosynthesis | Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | L-histidinol + phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homotetramer | 4 * 29976 | Thermus thermophilus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HisPPase | - |
Thermus thermophilus |
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Release 2023.1 (January 2023)
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