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Literature summary for 3.1.3.11 extracted from

  • Dang, Q.; Liu, Y.; Cashion, D.K.; Kasibhatla, S.R.; Jiang, T.; Taplin, F.; Jacintho, J.D.; Li, H.; Sun, Z.; Fan, Y.; Dare, J.; Tian, F.; Li, W.; Gibson, T.; Lemus, R.; van Poelje, P.D.; Potter, S.C.; Erion, M.D.
    Discovery of a series of phosphonic Acid-containing thiazoles and orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase (2011), J. Med. Chem., 54, 153-165.
    View publication on PubMed

Application

Application Comment Organism
drug development the enzyme is a target for drug development in treatment of type 2 diabetes mellitus Homo sapiens
medicine use of enzyme inhibitors in treatment of type 2 diabetes mellitus Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
(5-[2-amino-5-[(propylsulfanyl)carbonyl]-1,3-thiazol-4-yl]furan-2-yl)phosphonic acid
-
Homo sapiens
2-(2-thienyl)-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-(3-pyridyl)-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-acetamido-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-4-[1-(3-phosphono)phenyl]thiazole
-
Homo sapiens
2-amino-4-[2-(5-(1-(3-bromophenyl)-1,3-propyl)phosphono)-furanyl]-5-isobutyl-thiazole
-
Homo sapiens
2-amino-4-[2-(5-(O-phenyl)-(N-((S)-1-ethoxycarbonyl)ethyl)-phosphonamido)-furanyl]-5-isobutylthiazole
-
Homo sapiens
2-amino-4-[2-(5-bis(p-acetoxybenzyl)phosphono)furanyl]-5-isobutylthiazole
-
Homo sapiens
2-amino-4-[2-(5-diphenylphosphono)furanyl]-5-isobutylthiazole
-
Homo sapiens
2-amino-4-[2-(5-monophenyl-monoamino-phosphono)furanyl]-5-isobutylthiazole
-
Homo sapiens
2-amino-4-[2-(5-monophenylphosphono)furanyl]-5-isobutylthiazole
-
Homo sapiens
2-amino-4-[2-(6-phosphono)pyridyl]thiazole
-
Homo sapiens
2-amino-4-[2-[5-(1-(4-pyridyl)-1,3-propyl)phosphono]furanyl]-5-isobutylthiazole
-
Homo sapiens
2-amino-4-[2-[5-bis(1-(1-ethoxycarbonyloxy)ethyl)phosphono]-furanyl]-5-isobutyl-thiazole
-
Homo sapiens
2-amino-4-[2-[5-bis(ethoxycarbonyloxymethyl)phosphono]-furanyl]-5-isobutyl-thiazole
-
Homo sapiens
2-amino-4-[2-[5-bis(phenoxycarbonyloxymethyl)phosphono]-furanyl]-5-isobutyl-thiazole
-
Homo sapiens
2-amino-5-(2,2,2-trifluoroethyl)-4-[2-(5-phosphono)furanyl]-thiazole
-
Homo sapiens
2-amino-5-(2-furanyl)-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-(2-methoxyphenyl)-4-[2-(5-phosphono)furanyl]-thiazole
-
Homo sapiens
2-amino-5-(2-naphthyl)-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-(2-thienyl)-4-[(N-phosphonomethyl)carbamoyl]-thiazole
-
Homo sapiens
2-amino-5-(2-thienyl)-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-(3-methoxyphenyl)-4-[2-(5-phosphono)furanyl]-thiazole
-
Homo sapiens
2-amino-5-(4-acetylphenyl)-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-(4-chlorophenyl)-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-(4-fluorophenyl)-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-(4-methanesulfonyl)-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-(4-methoxycarbonylphenyl)-4-[2-(5-phosphono)-furanyl]thiazole
-
Homo sapiens
2-amino-5-(4-methoxyphenyl)-4-[2-(5-phosphono)furanyl]-thiazole
-
Homo sapiens
2-amino-5-(4-methylthiophenyl)-4-[2-(5-phosphono)furanyl]-thiazole
-
Homo sapiens
2-amino-5-(4-phenylphenyl)-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-(4-tert-butylphenyl)-4-[2-(5-phosphono)furanyl]-thiazole
-
Homo sapiens
2-amino-5-(N-morpholinyl)-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-benzyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-benzyloxycarbonyl-4-[2-(5-phosphono)furanyl]-thiazole
-
Homo sapiens
2-amino-5-bromo-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-chloro-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-cyclobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-cyclohexyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-cyclohexylmethyl-4-[2-(5-phosphono)furanyl]-thiazole
-
Homo sapiens
2-amino-5-cyclopentyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-cyclopentylmethyl-4-[2-(5-phosphono)furanyl]-thiazole
-
Homo sapiens
2-amino-5-cyclopropylmethyl-4-[2-(5-phosphono)furanyl]-thiazole
-
Homo sapiens
2-amino-5-ethylthio-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-hydroxymethyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-iodo-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-isopropyl- 4-[1-(4-methoxy-3-phosphono)phenyl]-thiazole
-
Homo sapiens
2-amino-5-isopropyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-isopropylthio-4-[2-(5-phosphono)furanyl]thiazole hydrobromide
-
Homo sapiens
2-amino-5-methyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-neopentyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-phenyl- 4-[1-(4-fluoro-3-phosphono)phenyl]thiazole
-
Homo sapiens
2-amino-5-phenyl-4-[2-(5-methyl-4-phosphono)oxazolyl]-thiazole
-
Homo sapiens
2-amino-5-phenyl-4-[3-(1-phosphono)pyrrolyl]thiazole
-
Homo sapiens
2-amino-5-phenylthio-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-propyl- 4-[1-(4-methyl-3-phosphono)phenyl]thiazole
-
Homo sapiens
2-amino-5-propyl-4-phosphonomethoxycarbonylthiazole
-
Homo sapiens
2-amino-5-propyl-4-[1-(3-phosphono)phenyl]thiazole
-
Homo sapiens
2-amino-5-propyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-tert-butylthio-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-amino-5-[(4-morpholinyl)methyl]-4-[2-(5-phosphono)furanyl]-thiazole dihydrobromide
-
Homo sapiens
2-amino-5-[(N,N-dimethyl)carbamoyl]-4-[2-(5-phosphono)-furanyl]thiazole
-
Homo sapiens
2-bromo-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-carbamoyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-chloro-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-cyano-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-ethyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-hydroxymethyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-methyl-5-isobutyl-4-[2-(5-phosphono)furanyl]-thiazole
-
Homo sapiens
2-methylamino-5-isobutyl-4-[2-(5-hosphono)furanyl]thiazole
-
Homo sapiens
2-methylthio-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-phenyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-thiocarbamoyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
2-vinyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
-
Homo sapiens
ethyl 4-[5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl]-2,2,6,6-tetramethyl-7-oxo-8-oxa-3,5-diaza-4-phosphadecan-1-oate 4-oxide (non-preferred name)
-
Homo sapiens
ethyl 4-[5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl]-2,6-dimethyl-7-oxo-8-oxa-3,5-diaza-4-phosphadecan-1-oate 4-oxide (non-preferred name)
-
Homo sapiens
ethyl 4-[5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl]-7-oxo-8-oxa-3,5-diaza-4-phosphadecan-1-oate 4-oxide (non-preferred name)
-
Homo sapiens
additional information synthesis and evaluation of a series of phosphonic acid-containing thiazoles as enzyme inhibitors, structure-guided drug design approach, optimization of both the thiazole FBPase inhibitors and their prodrugs, overview Homo sapiens
propan-2-yl 4-[5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl]-9-methyl-7-oxo-3,5,8-trioxa-4-phosphadecan-1-oate 4-oxide
-
Homo sapiens
tert-butyl 4-[5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl]-9,9-dimethyl-7-oxo-3,5,8-trioxa-4-phosphadecan-1-oate 4-oxide
-
Homo sapiens
[5-(2-amino-5-phenyl-1,3-thiazol-4-yl)furan-2-yl]phosphonic acid
-
Homo sapiens
[5-(2-amino-5-propyl-1,3-thiazol-4-yl)thiophen-2-yl]phosphonic acid
-
Homo sapiens
[5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl]phosphonic acid
-
Homo sapiens
[5-[2-amino-5-(ethoxycarbonyl)-1,3-thiazol-4-yl]furan-2-yl]phosphonic acid
-
Homo sapiens
[5-[2-amino-5-(propylsulfanyl)-1,3-thiazol-4-yl]furan-2-yl]phosphonic acid
-
Homo sapiens
[5-[5-(2-methylpropyl)-2-phenyl-1,3-thiazol-4-yl]furan-2-yl]phosphonic acid
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
FBPase
-
Homo sapiens
fructose-1,6-bisphosphatase
-
Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00001
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-cyclopropylmethyl-4-[2-(5-phosphono)furanyl]-thiazole
0.000012
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-cyclobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.000012
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(2-naphthyl)-4-[2-(5-phosphono)furanyl]thiazole
0.000013
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(4-chlorophenyl)-4-[2-(5-phosphono)furanyl]thiazole
0.000014
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens [5-[2-amino-5-(ethoxycarbonyl)-1,3-thiazol-4-yl]furan-2-yl]phosphonic acid
0.000014
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens [5-(2-amino-5-phenyl-1,3-thiazol-4-yl)furan-2-yl]phosphonic acid
0.000014
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(4-methoxycarbonylphenyl)-4-[2-(5-phosphono)-furanyl]thiazole
0.000015
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-benzyloxycarbonyl-4-[2-(5-phosphono)furanyl]-thiazole
0.000016
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(N-morpholinyl)-4-[2-(5-phosphono)furanyl]thiazole
0.000016
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens [5-[2-amino-5-(propylsulfanyl)-1,3-thiazol-4-yl]furan-2-yl]phosphonic acid
0.000016
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(4-fluorophenyl)-4-[2-(5-phosphono)furanyl]thiazole
0.000018
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-cyclohexylmethyl-4-[2-(5-phosphono)furanyl]-thiazole
0.000019
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-cyclopentyl-4-[2-(5-phosphono)furanyl]thiazole
0.00002
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-cyclopentylmethyl-4-[2-(5-phosphono)furanyl]-thiazole
0.000021
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-cyclohexyl-4-[2-(5-phosphono)furanyl]thiazole
0.000021
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(3-methoxyphenyl)-4-[2-(5-phosphono)furanyl]-thiazole
0.000021
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(4-methylthiophenyl)-4-[2-(5-phosphono)furanyl]-thiazole
0.000022
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(4-methoxyphenyl)-4-[2-(5-phosphono)furanyl]-thiazole
0.000024
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-isopropylthio-4-[2-(5-phosphono)furanyl]thiazole hydrobromide
0.000024
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-tert-butylthio-4-[2-(5-phosphono)furanyl]thiazole
0.000025
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens [5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl]phosphonic acid
0.000028
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(2,2,2-trifluoroethyl)-4-[2-(5-phosphono)furanyl]-thiazole
0.00003
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-isopropyl-4-[2-(5-phosphono)furanyl]thiazole
0.000032
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(4-acetylphenyl)-4-[2-(5-phosphono)furanyl]thiazole
0.000033
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-ethylthio-4-[2-(5-phosphono)furanyl]thiazole
0.000034
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(4-phenylphenyl)-4-[2-(5-phosphono)furanyl]thiazole
0.00004
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(2-furanyl)-4-[2-(5-phosphono)furanyl]thiazole
0.000041
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(4-methanesulfonyl)-4-[2-(5-phosphono)furanyl]thiazole
0.000043
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(2-methoxyphenyl)-4-[2-(5-phosphono)furanyl]-thiazole
0.000044
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(2-thienyl)-4-[2-(5-phosphono)furanyl]thiazole
0.00005
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-bromo-4-[2-(5-phosphono)furanyl]thiazole
0.000057
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-neopentyl-4-[2-(5-phosphono)furanyl]thiazole
0.000059
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-benzyl-4-[2-(5-phosphono)furanyl]thiazole
0.00007
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-chloro-4-[2-(5-phosphono)furanyl]thiazole
0.00008
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-bromo-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.000088
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(4-tert-butylphenyl)-4-[2-(5-phosphono)furanyl]-thiazole
0.0001
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-methyl-5-isobutyl-4-[2-(5-phosphono)furanyl]-thiazole
0.0001
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-iodo-4-[2-(5-phosphono)furanyl]thiazole
0.00012
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-hydroxymethyl-4-[2-(5-phosphono)furanyl]thiazole
0.00015
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-[(4-morpholinyl)methyl]-4-[2-(5-phosphono)furanyl]-thiazole dihydrobromide
0.00018
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-chloro-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.00022
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-hydroxymethyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.0003
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-phenylthio-4-[2-(5-phosphono)furanyl]thiazole
0.0004
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-ethyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.00045
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-methyl-4-[2-(5-phosphono)furanyl]thiazole
0.0005
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.0005
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-thiocarbamoyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.0005
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-propyl-4-[2-(5-phosphono)furanyl]thiazole
0.00056
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens [5-[5-(2-methylpropyl)-2-phenyl-1,3-thiazol-4-yl]furan-2-yl]phosphonic acid
0.000858
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens (5-[2-amino-5-[(propylsulfanyl)carbonyl]-1,3-thiazol-4-yl]furan-2-yl)phosphonic acid
0.00089
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-methylthio-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.001
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-methylamino-5-isobutyl-4-[2-(5-hosphono)furanyl]thiazole
0.0012
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-vinyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.0013
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-4-[1-(3-phosphono)phenyl]thiazole
0.0017
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-[(N,N-dimethyl)carbamoyl]-4-[2-(5-phosphono)-furanyl]thiazole
0.002
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-cyano-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.002
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-4-[2-(6-phosphono)pyridyl]thiazole
0.00275
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-carbamoyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.005
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(3-pyridyl)-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.008
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-(2-thienyl)-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.01
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-acetamido-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.01
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens [5-(2-amino-5-propyl-1,3-thiazol-4-yl)thiophen-2-yl]phosphonic acid
0.01
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-phenyl-4-[3-(1-phosphono)pyrrolyl]thiazole
0.01
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-phenyl-4-[2-(5-methyl-4-phosphono)oxazolyl]-thiazole
0.0135
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-phenyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiazole
0.05
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-propyl-4-phosphonomethoxycarbonylthiazole
0.08
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-phenyl- 4-[1-(4-fluoro-3-phosphono)phenyl]thiazole
0.135
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-propyl- 4-[1-(4-methyl-3-phosphono)phenyl]thiazole
0.21
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-isopropyl- 4-[1-(4-methoxy-3-phosphono)phenyl]-thiazole
0.25
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-propyl-4-[1-(3-phosphono)phenyl]thiazole
0.95
-
pH not specified in the publication, temperature not specified in the publication Homo sapiens 2-amino-5-(2-thienyl)-4-[(N-phosphonomethyl)carbamoyl]-thiazole