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Literature summary for 3.1.3.11 extracted from

  • Burenina, E.
    Fructose bisphosphatase of cestodes of Bothriocephalus scorpii (2010), J. Evol. Biochem. Physiol., 46, 153-162.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
4-chloromercuribenzoate activates in presence of Mg2+, inhibits in presence of Mn2+ Bothriocephalus scorpii
DTT activates in presence of Mg2+, inhibits in presence of Mn2+ Bothriocephalus scorpii

Inhibitors

Inhibitors Comment Organism Structure
ADP
-
Bothriocephalus scorpii
AMP
-
Bothriocephalus scorpii
ATP
-
Bothriocephalus scorpii
citrate
-
Bothriocephalus scorpii
Cu2+
-
Bothriocephalus scorpii
EDTA
-
Bothriocephalus scorpii
K+ inhibitory in the cytosol, activating in mitochondria and microsomes, depedent on the presence of Mg2+ or Mn2+, overview Bothriocephalus scorpii
Li+
-
Bothriocephalus scorpii
Na+
-
Bothriocephalus scorpii
NaF
-
Bothriocephalus scorpii
NH4+
-
Bothriocephalus scorpii
Zn2+
-
Bothriocephalus scorpii

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Bothriocephalus scorpii 5829
-
microsome
-
Bothriocephalus scorpii
-
-
mitochondrion
-
Bothriocephalus scorpii 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
K+ inhibitory in the cytosol, activating in mitochondria and microsomes, depedent on the presence of Mg2+ or Mn2+, overview Bothriocephalus scorpii
Mg2+ required at different concentrations in the different subcellular fractions, overview Bothriocephalus scorpii
Mn2+ required at different concentrations in the different subcellular fractions, overview Bothriocephalus scorpii
NH4+ activates Bothriocephalus scorpii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-fructose 1,6-bisphosphate + H2O Bothriocephalus scorpii
-
D-fructose 6-phosphate + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Bothriocephalus scorpii
-
parasitizing in pyloric appendages of the goby Myoxocephalus brandti
-

Source Tissue

Source Tissue Comment Organism Textmining
cestode
-
Bothriocephalus scorpii
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-fructose 1,6-bisphosphate + H2O
-
Bothriocephalus scorpii D-fructose 6-phosphate + phosphate
-
?

Synonyms

Synonyms Comment Organism
FBPase
-
Bothriocephalus scorpii
fructose bisphosphatase
-
Bothriocephalus scorpii

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
Bothriocephalus scorpii

General Information

General Information Comment Organism
metabolism fructose bisphosphatase is the key enzyme of gluconeogenesis Bothriocephalus scorpii