Literature summary for 3.1.3.11 extracted from

Gizak, A.; Maciaszczyk-Dziubinska, E.; Jurowicz, M.; Rakus, D.
Muscle FBPase is targeted to nucleus by its 203KKKGK207 sequence (2009), Proteins, 77, 262-267.

Search for more literature for 3.1.3.11

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
K203E	mutation results in a noticeable drop in the amount of cells having nuclear FBPase	Homo sapiens
K204E	mutation results in a noticeable drop in the amount of cells having nuclear FBPase	Homo sapiens
K205E	mutation results in a noticeable drop in the amount of cells having nuclear FBPase	Homo sapiens
K207E	mutation results in a noticeable drop in the amount of cells having nuclear FBPase	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
nucleus	integrity of the 203KKKGK207 motif is crucial to nuclear targeting. Even a single amino-acid change within this sequence results in significant decrease of nuclear accumulation of the enzyme	Homo sapiens	5634	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
muscle	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
FBPase	-	Homo sapiens
fructose 1,6-bisphosphatase	-	Homo sapiens

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Release 2023.1 (January 2023)