Protein Variants | Comment | Organism |
---|---|---|
E280Q | K+ loses the ability to activate and became a noncompetitive inhibitor | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Li+ | linear competitive inhibitor | Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
K+ | activates | Sus scrofa | |
K+ | Km: 17 mM | Sus scrofa | |
additional information | monovalent cations activate by helping the Arg 276 residue "deshield" the partial negative charge on the 1-phosphoryl group of the substrate so that nucleophilic attack on the 1-phosphorus atom is facilitated | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-fructose 1,6-diphosphate + H2O | - |
Sus scrofa | D-fructose 6-phosphate + phosphate | - |
? |